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Merkel Cell Carcinoma of Skin

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●Neuroendocrine carcinoma of the skin

●Source: Merkel cells in the skin. 

●It is a rare skin cancer with roughly 1500 cases per year.

●Merkel cell polyomavirus is strongly associated

●Presentation: Painless, firm, flesh-colored to red or blue bump 

Prognosis: Merkel cell tumor, highly malignant and usually fatal.

●Morphology: Looks EXACTLY like a small cell carcinoma of the lung with small blue round cells, high N:C ratio, nuclear irregularity, nuclear molding.

Merkel Cell Carcinoma-Tumor nodule

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